RABL2B Gene Summary [Human]
The RABL2B protein is a member of the RAB gene family which belongs to the RAS GTPase superfamily. RABL2B is located within a subtelomeric region of 22q13.3. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Details
| Type | Protein Coding |
| Official Symbol | RABL2B |
| Official Name | RAB, member of RAS oncogene family like 2B [Source:HGNC Symbol;Acc:HGNC:9800] |
| Ensembl ID | ENSG00000079974 |
| Bio databases IDs | |
| Aliases | RAB, member of RAS oncogene family like 2B |
| Synonyms | 1110031N17Rik, Rabl2, Rabl2a, RAB, member of RAS oncogene family like 2, RAB, member of RAS oncogene family like 2B, RAB, member RAS oncogene family-like 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RABL2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- small GTP-binding protein domain
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- Rab subfamily of small GTPases
- GTPase
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- basal bodies
- centrosome
- centriole
- sperm midpiece
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RABL2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- intraflagellar transport
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- pericentriolar material
- cilium basal body
- centriole
- cytoplasm
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity