SLC35C2 Gene Summary [Human]
This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
Details
| Type | Protein Coding |
| Official Symbol | SLC35C2 |
| Official Name | solute carrier family 35 member C2 [Source:HGNC Symbol;Acc:HGNC:17117] |
| Ensembl ID | ENSG00000080189 |
| Bio databases IDs | |
| Aliases | solute carrier family 35 member C2 |
| Synonyms | BA394O2.1, C20orf5, CGI-15, D2Wsu58e, LOC100128167, OVCOV1, solute carrier family 35 member C2, solute carrier family 35, member C2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC35C2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Triose-phosphate Transporter family
- UAA transporter family
- Tpt phosphate/phosphoenolpyruvate translocator
- protein binding
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- ER-to-Golgi intermediate compartment
- cis Golgi networks
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC35C2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- UDP-glucose transport
- negative regulation of gene expression
- protein O-linked fucosylation
- positive regulation of Notch signaling pathway
Cellular Component
Where in the cell the gene product is active
- cis-Golgi network
- Golgi apparatus
- endoplasmic reticulum-Golgi intermediate compartment
- endoplasmic reticulum-Golgi intermediate compartment membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- antiporter activity