Slc35c2 Gene Summary [Mouse]

Predicted to enable antiporter activity. Acts upstream of or within negative regulation of gene expression; positive regulation of Notch signaling pathway; and protein O-linked fucosylation. Predicted to be located in nucleoplasm. Predicted to be active in cis-Golgi network and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and gonad. Orthologous to human SLC35C2 (solute carrier family 35 member C2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc35c2
Official Name
solute carrier family 35, member C2 [Source:MGI Symbol;Acc:MGI:2385166]
Ensembl ID
ENSMUSG00000017664
Bio databases IDs NCBI: 228875 Ensembl: ENSMUSG00000017664
Aliases solute carrier family 35, member C2
Synonyms BA394O2.1, C20orf5, CGI-15, D2Wsu58e, LOC100128167, OVCOV1, solute carrier family 35 member C2, solute carrier family 35, member C2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc35c2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Triose-phosphate Transporter family
  • UAA transporter family
  • Tpt phosphate/phosphoenolpyruvate translocator
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • growth failure
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Golgi Apparatus
  • ER-to-Golgi intermediate compartment
  • cis Golgi networks
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc35c2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • UDP-glucose transport
  • negative regulation of gene expression
  • protein O-linked fucosylation
  • positive regulation of Notch signaling pathway

Cellular Component

Where in the cell the gene product is active
  • cis-Golgi network
  • Golgi apparatus
  • endoplasmic reticulum-Golgi intermediate compartment
  • endoplasmic reticulum-Golgi intermediate compartment membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • antiporter activity

Gene-Specific Assays for Results You Can Trust

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