RSBN1 Gene Summary [Human]

Predicted to enable dioxygenase activity and metal ion binding activity. Predicted to be involved in chromatin organization. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RSBN1
Official Name
round spermatid basic protein 1 [Source:HGNC Symbol;Acc:HGNC:25642]
Ensembl ID
ENSG00000081019
Bio databases IDs NCBI: 54665 Ensembl: ENSG00000081019
Aliases round spermatid basic protein 1
Synonyms C230004D03Rik, E330004N01, FLJ11220, KDM9, mKIAA3002, RGD1307231, ROSBIN, rosbin, round spermatid basic protein 1, round spermatid basic protein 1, Rsbn, Rsbp
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RSBN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 2-oxoglutarate:oxygen oxidoreductase
  • enzyme
  • protein binding
  • histone demethylase activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • hypothyroidism
  • coronary artery disease
  • myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RSBN1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • histone demethylase activity (H4-K20 specific)
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.