Rsbn1 Gene Summary [Mouse]

Enables histone H4K20 demethylase activity. Predicted to be involved in chromatin remodeling. Located in nucleus. Is expressed in metanephros; oviduct; testis; and thymus. Orthologous to human RSBN1 (round spermatid basic protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rsbn1
Official Name
rosbin, round spermatid basic protein 1 [Source:MGI Symbol;Acc:MGI:2444993]
Ensembl ID
ENSMUSG00000044098
Bio databases IDs NCBI: 229675 Ensembl: ENSMUSG00000044098
Aliases rosbin, round spermatid basic protein 1
Synonyms C230004D03Rik, E330004N01, FLJ11220, KDM9, mKIAA3002, RGD1307231, ROSBIN, rosbin, round spermatid basic protein 1, round spermatid basic protein 1, Rsbn, Rsbp
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rsbn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 2-oxoglutarate:oxygen oxidoreductase
  • enzyme
  • protein binding
  • histone demethylase activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • hypothyroidism
  • coronary artery disease
  • myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
regulated by
  • CD24
  • Bacillus anthracis strain Sterne
  • PIWIL4

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rsbn1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • histone demethylase activity (H4-K20 specific)
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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