WDR70 Gene Summary [Human]
Enables enzyme binding activity. Predicted to be involved in regulation of DNA double-strand break processing and regulation of histone H2B conserved C-terminal lysine ubiquitination. Predicted to be active in nucleus and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | WDR70 |
| Official Name | WD repeat domain 70 [Source:HGNC Symbol;Acc:HGNC:25495] |
| Ensembl ID | ENSG00000082068 |
| Bio databases IDs | |
| Aliases | WD repeat domain 70 |
| Synonyms | 4833422F06Rik, FLJ10233, RGD1309487, WD repeat domain 70 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WDR70 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- enzyme binding
- WD40
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human WDR70 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- site of double-strand break
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- enzyme binding