Wdr70 Gene Summary [Mouse]

Predicted to enable enzyme binding activity. Predicted to be active in nucleus and site of double-strand break. Orthologous to human WDR70 (WD repeat domain 70). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Wdr70
Official Name
WD repeat domain 70 [Source:MGI Symbol;Acc:MGI:1921020]
Ensembl ID
ENSMUSG00000039828
Bio databases IDs NCBI: 545085 Ensembl: ENSMUSG00000039828
Aliases WD repeat domain 70
Synonyms 4833422F06Rik, FLJ10233, RGD1309487, WD repeat domain 70
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr70 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • enzyme binding
  • WD40

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • widespread chronic pain
  • late-onset Alzheimer disease
  • diverticular disease
regulated by
  • phosphate
  • crocin
  • FN1
  • Rpmi 8226 cells
  • camptothecin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr70 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • site of double-strand break
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • enzyme binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.