KIF3C Gene Summary [Human]
Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to act upstream of or within organelle transport along microtubule. Predicted to be located in microtubule cytoskeleton; neuronal cell body; and neuronal ribonucleoprotein granule. Predicted to be part of kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | KIF3C |
| Official Name | kinesin family member 3C [Source:HGNC Symbol;Acc:HGNC:6321] |
| Ensembl ID | ENSG00000084731 |
| Bio databases IDs | |
| Aliases | kinesin family member 3C |
| Synonyms | kinesin family member 3C, mKIAA4058 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KIF3C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinesin motor, catalytic domain
- microtubule binding
- Myosin and Kinesin motor domain
- Kinesin motor domain
- tail domain
- protein binding
- motor domain
- motor protein
- kinesin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- atrial fibrillation
- non-insulin-dependent diabetes mellitus
- hereditary gingival fibromatosis
- infection by HIV-1
- productive infection by HIV-1
role in cell
- proliferation
- expression in
- migration
- regeneration
- development
- instability
- regeneration in
- stabilization in
- outgrowth in
- stabilization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microsomal fraction
- microtubule cytoskeleton
- cytoplasmic ribonucleoprotein granule
- ciliary tip
- cilia
- microtubules
- cytosol
- synaptic vesicles
- growth cone
- plus end of microtubule
- membrane processes
- perikaryon
- axons
- dendrites
- vesicle fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KIF3C gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- cilium
- cytosol
- kinesin complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- microtubule motor activity
- protein binding
- microtubule binding
- motor activity