ERGIC2 Gene Summary [Human]
ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
Details
| Type | Protein Coding |
| Official Symbol | ERGIC2 |
| Official Name | ERGIC and golgi 2 [Source:HGNC Symbol;Acc:HGNC:30208] |
| Ensembl ID | ENSG00000087502 |
| Bio databases IDs | |
| Aliases | ERGIC and golgi 2 |
| Synonyms | 1200009B18Rik, 4930572C01Rik, cd002, CDA14, ERGIC and golgi 2, Erv41, LOC120102435, PTX1, RGD1310606 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ERGIC2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Nucleus
- Golgi Apparatus
- ER-to-Golgi intermediate compartment
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ERGIC2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- retrograde vesicle-mediated transport, Golgi to ER
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nucleus
- cytoplasm
- intracellular membrane-bounded organelle
- membrane
- endoplasmic reticulum
- Golgi apparatus
- ER to Golgi transport vesicle
- nucleolus
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding