CDIP1 Gene Summary [Human]
Predicted to enable metal ion binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and tumor necrosis factor-mediated signaling pathway. Located in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CDIP1 |
| Official Name | cell death inducing p53 target 1 [Source:HGNC Symbol;Acc:HGNC:13234] |
| Ensembl ID | ENSG00000089486 |
| Bio databases IDs | |
| Aliases | cell death inducing p53 target 1, cell death involved p53-target, lipopolysaccharide-induced TNF factor-like |
| Synonyms | 2700048O17Rik, 5730403B10Rik, C16orf5, CDIP, cell death-inducing p53 target 1, cell death inducing Trp53 target 1, I1, LITAFL, RGD1310686 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDIP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- LITAF-like zinc ribbon domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CDIP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding