HAUS4 Gene Summary [Human]
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Details
| Type | Protein Coding |
| Official Symbol | HAUS4 |
| Official Name | HAUS augmin like complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:20163] |
| Ensembl ID | ENSG00000092036 |
| Bio databases IDs | |
| Aliases | HAUS augmin like complex subunit 4 |
| Synonyms | 9430093H08Rik, C14orf94, D14Ertd500e, HAUS augmin like complex subunit 4, HAUS augmin-like complex, subunit 4, RGD1305288 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HAUS4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HAUS augmin-like complex subunit 4
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- cytosol
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HAUS4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle assembly
- centrosome cycle
- regulation of microtubule nucleation
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytosol
- HAUS complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule minus-end binding