HAUS7 Gene Summary [Human]
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Details
| Type | Protein Coding |
| Official Symbol | HAUS7 |
| Official Name | HAUS augmin like complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:32979] |
| Ensembl ID | ENSG00000213397 |
| Bio databases IDs | |
| Aliases | HAUS augmin like complex subunit 7, UCH37 interacting protein 1, 26S proteasome-associated UCH interacting protein 1 |
| Synonyms | 1110020L19Rik, HAUS augmin like complex subunit 7, HAUS augmin-like complex, subunit 7, RGD1562991, UCHL5IP, UIP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HAUS7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- basal bodies
- centrosome
- cytosol
- nucleoli
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HAUS7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle assembly
- centrosome cycle
- regulation of microtubule nucleation
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytosol
- HAUS complex
- nucleolus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule minus-end binding
- thioesterase binding