ADNP2 Gene Summary [Human]
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in several processes, including cellular response to oxidative stress; cellular response to retinoic acid; and positive regulation of cell growth. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ADNP2 |
| Official Name | ADNP homeobox 2 [Source:HGNC Symbol;Acc:HGNC:23803] |
| Ensembl ID | ENSG00000101544 |
| Bio databases IDs | |
| Aliases | ADNP homeobox 2 |
| Synonyms | 8430420L05Rik, ADNP homeobox 2, Kiaa0863, LOC100506109, mKIAA0863, RGD1308279, Zfp508, ZNF508 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ADNP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4813)
- Solibacter uncharacterized C-terminal domain
- RNA polymerase II transcription factor activity, sequence-specific DNA binding
- Family of unknown function (DUF5585)
- transcription regulator
- Activity-dependent neuroprotector homeobox protein N-terminal
- protein binding
- N-terminal domain of transcription factor Specificity Proteins (SP) 1-4
- homeodomain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ADNP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of gene expression
- nervous system development
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity