VPS35L Gene Summary [Human]
Involved in Golgi to plasma membrane transport and endocytic recycling. Located in endosome. Implicated in Ritscher-Schinzel syndrome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | VPS35L |
| Official Name | VPS35 endosomal protein sorting factor like [Source:HGNC Symbol;Acc:HGNC:24641] |
| Ensembl ID | ENSG00000103544 |
| Bio databases IDs | |
| Aliases | VPS35 endosomal protein sorting factor like |
| Synonyms | 2610029J22Rik, 9030624J02Rik, C16orf62, EC97, RTSC3, VPS35 endosomal protein sorting factor like, Vsp35l |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human VPS35L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- endosomes
- secretory granule membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human VPS35L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- Golgi to plasma membrane transport
- endocytic recycling
Cellular Component
Where in the cell the gene product is active
- endosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding