Vps35l Gene Summary [Mouse]
Predicted to be involved in Golgi to plasma membrane transport and endocytic recycling. Predicted to be located in membrane. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Orthologous to human VPS35L (VPS35 endosomal protein sorting factor like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vps35l |
| Official Name | VPS35 endosomal protein sorting factor like [Source:MGI Symbol;Acc:MGI:1918767] |
| Ensembl ID | ENSMUSG00000030982 |
| Bio databases IDs | |
| Aliases | VPS35 endosomal protein sorting factor like |
| Synonyms | 2610029J22Rik, 9030624J02Rik, C16orf62, EC97, RTSC3, VPS35 endosomal protein sorting factor like, Vsp35l |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vps35l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- endosomes
- secretory granule membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Vps35l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- Golgi to plasma membrane transport
- endocytic recycling
Cellular Component
Where in the cell the gene product is active
- endosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding