HUNK Gene Summary [Human]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | HUNK |
| Official Name | hormonally up-regulated Neu-associated kinase [Source:HGNC Symbol;Acc:HGNC:13326] |
| Ensembl ID | ENSG00000142149 |
| Bio databases IDs | |
| Aliases | hormonally up-regulated Neu-associated kinase |
| Synonyms | Bstk1, hormonally up-regulated Neu-associated kinase, Mak-v, RGD1565091 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HUNK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- protein kinase
- Protein Kinases, catalytic domain
- protein binding
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- non-insulin-dependent diabetes mellitus
- cancer
- Crohn disease
- advanced cancer
- periodontitis
- measles
- vitiligo
role in cell
- migration
- differentiation
- expression in
- proliferation
- phosphorylation in
- apoptosis
- binding in
- activation in
- invasion by
- polymerization in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HUNK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- intracellular signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- protein serine/threonine kinase activity