CCDC61 Gene Summary [Human]
Enables identical protein binding activity and microtubule binding activity. Involved in centriole assembly and mitotic spindle assembly. Located in centriolar satellite and ciliary basal body. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CCDC61 |
| Official Name | coiled-coil domain containing 61 [Source:HGNC Symbol;Acc:HGNC:33629] |
| Ensembl ID | ENSG00000104983 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 61, variable flagellar number 3 homolog (C. reinhardtii) |
| Synonyms | C530028I08Rik, coiled-coil domain containing 61, Gm159, hVFL3, LOC388554, RGD1307390, VFL3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCDC61 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- protein binding
- N-terminal head domain found in the XRCC4 superfamily of proteins
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- basal bodies
- centrosome
- microtubule organizing centers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CCDC61 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell projection organization
- spindle assembly involved in mitosis
Cellular Component
Where in the cell the gene product is active
- centrosome
- microtubule organizing center
- cytoplasm
- cilium basal body
- centriolar satellite
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- microtubule binding