FSD1 Gene Summary [Human]
This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq, Apr 2009]
Details
| Type | Protein Coding |
| Official Symbol | FSD1 |
| Official Name | fibronectin type III and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13745] |
| Ensembl ID | ENSG00000105255 |
| Bio databases IDs | |
| Aliases | fibronectin type III and SPRY domain containing 1 |
| Synonyms | fibronectin type 3 and SPRY domain-containing protein, fibronectin type III and SPRY domain containing 1, Fsd1l1, GLFND, MGC58341, MIR1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FSD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
- microtubule binding
- B-Box C-terminal domain
- SPRY domain
- FN3
- RGD motif
- coiled-coil domain
- Fibronectin type 3 domain
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- microtubules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FSD1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of cell division
- regulation of cytokinesis
- cytoplasmic microtubule organization
- regulation of mitotic spindle organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cleavage furrow
- cytoplasm
- microtubule
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- microtubule binding