Fsd1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity and microtubule binding activity. Predicted to be involved in cytoplasmic microtubule organization; regulation of cytokinesis; and regulation of mitotic spindle organization. Predicted to be located in centrosome. Predicted to be active in microtubule. Is expressed in nervous system and sensory organ. Orthologous to human FSD1 (fibronectin type III and SPRY domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Fsd1 |
| Official Name | fibronectin type 3 and SPRY domain-containing protein [Source:MGI Symbol;Acc:MGI:1934858] |
| Ensembl ID | ENSMUSG00000011589 |
| Bio databases IDs | |
| Aliases | fibronectin type 3 and SPRY domain-containing protein |
| Synonyms | fibronectin type 3 and SPRY domain-containing protein, fibronectin type III and SPRY domain containing 1, Fsd1l1, GLFND, MGC58341, MIR1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fsd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
- microtubule binding
- B-Box C-terminal domain
- SPRY domain
- FN3
- RGD motif
- coiled-coil domain
- Fibronectin type 3 domain
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- microtubules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fsd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of cell division
- regulation of cytokinesis
- cytoplasmic microtubule organization
- regulation of mitotic spindle organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cleavage furrow
- cytoplasm
- microtubule
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- microtubule binding