RNF32 Gene Summary [Human]

The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Details

Type
Protein Coding
Official Symbol
RNF32
Official Name
ring finger protein 32 [Source:HGNC Symbol;Acc:HGNC:17118]
Ensembl ID
ENSG00000105982
Bio databases IDs NCBI: 140545 Ensembl: ENSG00000105982
Aliases ring finger protein 32
Synonyms 1700009J01Rik, 2700025B22Rik, 4930542N22Rik, FKSG33, HSD15, LMBR2, ring finger protein 32
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNF32 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calmodulin-binding motif
  • IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
  • RING-type zinc-finger
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • Ring finger domain
  • protein binding
  • RING-like zinc finger
  • RING-H2 zinc finger domain
  • Zinc finger, C3HC4 type (RING finger)
  • zinc-RING finger domain
  • IQ calmodulin-binding motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • aggresome
  • endosomes
  • cytosol
  • nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RNF32 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nuclear body
  • endosome
  • cytosol
  • aggresome

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.