MOGAT3 Gene Summary [Human]
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | MOGAT3 |
| Official Name | monoacylglycerol O-acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:23249] |
| Ensembl ID | ENSG00000106384 |
| Bio databases IDs | |
| Aliases | monoacylglycerol O-acyltransferase 3 |
| Synonyms | DC7, DGAT2L2, Gm26989, MGAT3, monoacylglycerol O-acyltransferase 3, predicted gene, 26989 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MOGAT3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
- 2-acylglycerol O-acyltransferase
- diacylglycerol O-acyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MOGAT3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycerol metabolic process
- triglyceride biosynthetic process
- monoacylglycerol biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- 2-acylglycerol O-acyltransferase activity
- diacylglycerol O-acyltransferase activity