S100A7A Gene Summary [Human]

Enables protein self-association. Predicted to act upstream of or within inflammatory response. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
S100A7A
Official Name
S100 calcium binding protein A7A [Source:HGNC Symbol;Acc:HGNC:21657]
Ensembl ID
ENSG00000184330
Bio databases IDs NCBI: 338324 Ensembl: ENSG00000184330
Aliases S100 calcium binding protein A7A, koebnerisin
Synonyms NICE-2, S100A15, S100A7f, S100A7L1, S100 calcium binding protein A7A
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human S100A7A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • S-100/ICaBP type calcium binding domain
  • EFh
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • cholesteatoma
  • plaque psoriasis
  • mastocytosis
regulated by
regulates
role in cell
  • chemotaxis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human S100A7A gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • transition metal ion binding
  • protein binding
  • calcium ion binding
  • calcium-dependent protein binding

Gene-Specific Assays for Results You Can Trust

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