ANAPC15 Gene Summary [Human]
Involved in regulation of mitotic cell cycle spindle assembly checkpoint. Part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ANAPC15 |
| Official Name | anaphase promoting complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:24531] |
| Ensembl ID | ENSG00000110200 |
| Bio databases IDs | |
| Aliases | anaphase promoting complex subunit 15 |
| Synonyms | 3200002M19Rik, 6330414C15Rik, anaphase promoting complex C subunit 15, anaphase promoting complex subunit 15, APC15, C11orf51, HSPC020, RGD1311634 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANAPC15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ANAPC15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of meiotic cell cycle
- protein K11-linked ubiquitination
- protein K48-linked ubiquitination
- regulation of mitotic cell cycle spindle assembly checkpoint
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
- regulation of mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- anaphase-promoting complex
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding