NAA40 Gene Summary [Human]

Enables H2A histone acetyltransferase activity; H4 histone acetyltransferase activity; and peptide-serine-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; histone H2A acetylation; and histone H4 acetylation. Located in centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Retained Intron
Official Symbol
NAA40
Official Name
N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845]
Ensembl ID
ENSG00000110583
Bio databases IDs NCBI: 79829 Ensembl: ENSG00000110583
Aliases N-alpha-acetyltransferase 40, NatD catalytic subunit
Synonyms 4931433E08Rik, hNatD, N-alpha-acetyltransferase 40, NatD catalytic subunit, N(alpha)-acetyltransferase 40, NatD catalytic subunit, NAT11, NatD, N-α-acetyltransferase 40, NatD catalytic subunit, N(α)-acetyltransferase 40, NatD catalytic subunit, PATT1, RGD1565838
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAA40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • histone acetyltransferase
  • Acetyltransferase (GNAT) family
  • peptide alpha-N-acetyltransferase
  • NAT_SF
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • lipid
  • fatty acid
  • triacylglycerol
role in cell
  • accumulation in
  • synthesis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human NAA40 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling
  • lipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • centriolar satellite
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • H4 histone acetyltransferase activity
  • H2A histone acetyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.