ARMC8 Gene Summary [Human]
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytosol and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ARMC8 |
| Official Name | armadillo repeat containing 8 [Source:HGNC Symbol;Acc:HGNC:24999] |
| Ensembl ID | ENSG00000114098 |
| Bio databases IDs | |
| Aliases | armadillo repeat containing 8, GID complex subunit 5, VID28 homolog (S. cerevisiae) |
| Synonyms | 1200015K23Rik, armadillo repeat containing 8, GID5, HSPC056, RGD1310477, S863-2, VID28 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARMC8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- secretory granule lumen
- Cytoplasm
- Extracellular Space
- organelle lumens
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARMC8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- ubiquitin ligase complex
- specific granule lumen
- cytoplasm
- intracellular membrane-bounded organelle
- cytosol
- extracellular region
- GID complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding