PHTF1 Gene Summary [Human]

Predicted to be located in cis-Golgi network and endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
PHTF1
Official Name
putative homeodomain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:8939]
Ensembl ID
ENSG00000116793
Bio databases IDs NCBI: 10745 Ensembl: ENSG00000116793
Aliases putative homeodomain transcription factor 1
Synonyms LOC102555542, Phft, PHTF, putative homeodomain transcription factor 1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PHTF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Homeodomain containing protein PHTF1/2, N-terminal

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypothyroidism
regulated by
  • dexamethasone
  • NUPR1
  • CREB
  • filgrastim
  • garcinol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cellular membrane
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PHTF1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cis-Golgi network membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.