ANKRD13C Gene Summary [Human]
Enables signaling receptor binding activity. Involved in protein retention in ER lumen; regulation of anoikis; and regulation of signaling receptor activity. Located in perinuclear region of cytoplasm. Colocalizes with endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ANKRD13C |
| Official Name | ankyrin repeat domain 13C [Source:HGNC Symbol;Acc:HGNC:25374] |
| Ensembl ID | ENSG00000118454 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 13C |
| Synonyms | AI505652, ankyrin repeat domain 13C, AU022220, dJ677H15.3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD13C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- Ankyrin repeats (3 copies)
- protein binding
- receptor binding
- GPCR-chaperone
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ANKRD13C gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of anoikis
- regulation of receptor activity
- protein retention in ER lumen
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- perinuclear region of cytoplasm
- cytoplasm
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- receptor binding