OLFM3 Gene Summary [Human]
Predicted to be involved in eye photoreceptor cell development. Predicted to be located in Golgi apparatus; extracellular space; and synapse. Predicted to be part of AMPA glutamate receptor complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | OLFM3 |
| Official Name | olfactomedin 3 [Source:HGNC Symbol;Acc:HGNC:17990] |
| Ensembl ID | ENSG00000118733 |
| Bio databases IDs | |
| Aliases | olfactomedin 3, optimedin |
| Synonyms | B230206G02Rik, NOE3, NOELIN3, olfactomedin 3, OPTIMEDIN |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OLFM3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Olfactomedin-like domain
- Neurogenesis glycoprotein
- C-terminal coiled-coil domain found in the laminin subunit beta (LAMB) family
- protein binding
- Glycosyl hydrolase families: GH43, GH62, GH32, GH68, GH117, CH130
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- perinuclear region
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OLFM3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- eye photoreceptor cell development
Cellular Component
Where in the cell the gene product is active
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
- extracellular space
- Golgi apparatus
- synapse
Molecular Function
What the gene product does at the molecular level
- protein binding