Olfm3 Gene Summary [Mouse]

Predicted to be involved in eye photoreceptor cell development and signal transduction. Located in Golgi apparatus and extracellular space. Part of AMPA glutamate receptor complex. Is expressed in brain; eye; and head. Orthologous to human OLFM3 (olfactomedin 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Olfm3
Official Name
olfactomedin 3 [Source:MGI Symbol;Acc:MGI:2387329]
Ensembl ID
ENSMUSG00000027965
Bio databases IDs NCBI: 229759 Ensembl: ENSMUSG00000027965
Aliases olfactomedin 3
Synonyms B230206G02Rik, NOE3, NOELIN3, olfactomedin 3, OPTIMEDIN
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Olfm3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Olfactomedin-like domain
  • Neurogenesis glycoprotein
  • C-terminal coiled-coil domain found in the laminin subunit beta (LAMB) family
  • protein binding
  • Glycosyl hydrolase families: GH43, GH62, GH32, GH68, GH117, CH130

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • major depression
  • cleft lip
  • Parkinson disease
regulated by
  • OLFM3
  • SOD1
  • cerebellar granule cell
  • tacrolimus
  • MYOC
  • n-nitrosomethylbenzylamine
  • DNMT1
  • black raspberry extract
regulates
role in cell
  • development

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Extracellular Space
  • perinuclear region
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Olfm3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • eye photoreceptor cell development

Cellular Component

Where in the cell the gene product is active
  • alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
  • extracellular space
  • Golgi apparatus
  • synapse

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.