PDZD11 Gene Summary [Human]
Enables protein C-terminus binding activity. Involved in pore complex assembly. Located in basolateral plasma membrane and cytosol. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PDZD11 |
| Official Name | PDZ domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28034] |
| Ensembl ID | ENSG00000120509 |
| Bio databases IDs | |
| Aliases | PDZ domain containing 11 |
| Synonyms | 1810012H22Rik, 2310079D11RIK, 2700099C19Rik, AIPP1, PDZ domain containing 11, PDZK11, PISP, RGD1560007 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PDZD11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain present in PSD-95, Dlg, and ZO-1/2
- canonical PDZ domain
- protein binding
- PDZ domain
- enzyme activator activity
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
- cytosol
- lateral cell surfaces
- basolateral membrane
- anchoring junction
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PDZD11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maintenance of epithelial cell apical/basal polarity
- pore complex assembly
- neurotransmitter secretion
Cellular Component
Where in the cell the gene product is active
- adherens junction
- cell-cell junction
- pore complex
- cytosol
- synapse
- extracellular region
- basolateral plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding