MTERF2 Gene Summary [Human]

Enables DNA binding activity. Predicted to be involved in termination of mitochondrial transcription. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MTERF2
Official Name
mitochondrial transcription termination factor 2 [Source:HGNC Symbol;Acc:HGNC:30779]
Ensembl ID
ENSG00000120832
Bio databases IDs NCBI: 80298 Ensembl: ENSG00000120832
Aliases mitochondrial transcription termination factor 2
Synonyms 1700007D05Rik, mitochondrial transcription termination factor 2, MTERFD3, mTERFL, RGD1311836
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MTERF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • mTERF
  • transcription regulator
  • protein binding
  • DNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial nucleoids

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MTERF2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • termination of mitochondrial transcription
  • regulation of transcription, DNA-dependent

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial nucleoid

Molecular Function

What the gene product does at the molecular level
  • nucleic acid binding
  • DNA binding
  • protein binding
  • double-stranded DNA binding

Gene-Specific Assays for Results You Can Trust

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