TMEM131L Gene Summary [Human]
Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of immature T cell proliferation in thymus. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM131L |
| Official Name | transmembrane 131 like [Source:HGNC Symbol;Acc:HGNC:29146] |
| Ensembl ID | ENSG00000121210 |
| Bio databases IDs | |
| Aliases | transmembrane 131 like |
| Synonyms | D930015E06Rik, KIAA0922, LOC683642, mKIAA0922, RGD1305449, transmembrane 131 like |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM131L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transmembrane protein 131-like N-terminal
- Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
- Transmembrane protein 131-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM131L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of canonical Wnt receptor signaling pathway
- negative regulation of immature T cell proliferation in thymus
- Wnt receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- endoplasmic reticulum
- plasma membrane