Tmem131l Gene Summary [Mouse]
Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of immature T cell proliferation in thymus. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human TMEM131L (transmembrane 131 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem131l |
| Official Name | transmembrane 131 like [Source:MGI Symbol;Acc:MGI:2443399] |
| Ensembl ID | ENSMUSG00000033767 |
| Bio databases IDs | |
| Aliases | transmembrane 131 like |
| Synonyms | D930015E06Rik, KIAA0922, LOC683642, mKIAA0922, RGD1305449, transmembrane 131 like |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem131l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transmembrane protein 131-like N-terminal
- Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
- Transmembrane protein 131-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem131l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of canonical Wnt receptor signaling pathway
- negative regulation of immature T cell proliferation in thymus
- Wnt receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- endoplasmic reticulum
- plasma membrane