OBP2A Gene Summary [Human]

This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport small, hydrophobic, volatile molecules or odorants through the nasal mucus to olfactory receptors, and may also function as a scavenger of highly concentrated or toxic odors. The protein is expressed as a monomer in the nasal mucus, and can bind diverse types of odorants with a higher affinity for aldehydes and fatty acids. This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Details

Type
Nonsense Mediated Decay
Official Symbol
OBP2A
Official Name
odorant binding protein 2A [Source:HGNC Symbol;Acc:HGNC:23380]
Ensembl ID
ENSG00000122136
Bio databases IDs NCBI: 29991 Ensembl: ENSG00000122136
Aliases odorant binding protein 2A
Synonyms hOBPIIa, LCN13, OBP, OBP2C, OBPIIa, odorant binding protein 2A
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OBP2A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • lipocalin/cytosolic fatty acid-binding protein family
  • Lipocalin / cytosolic fatty-acid binding protein family
  • odorant binding

Pathways

Biological processes and signaling networks where the OBP2A gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • prostate cancer

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human OBP2A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sensory perception of chemical stimulus
  • sensory perception of smell
  • glucose homeostasis

Cellular Component

Where in the cell the gene product is active
  • extracellular space

Molecular Function

What the gene product does at the molecular level
  • odorant binding
  • small molecule binding

Gene-Specific Assays for Results You Can Trust

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