Lypd3 Gene Summary [Mouse]
Predicted to enable laminin binding activity. Predicted to be involved in negative regulation of smooth muscle cell apoptotic process. Predicted to act upstream of or within cell motility and cell-matrix adhesion. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epithelium; foregut; sensory organ; skin; and thymus. Orthologous to human LYPD3 (LY6/PLAUR domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lypd3 |
| Official Name | Ly6/Plaur domain containing 3 [Source:MGI Symbol;Acc:MGI:1919684] |
| Ensembl ID | ENSMUSG00000057454 |
| Bio databases IDs | |
| Aliases | Ly6/Plaur domain containing 3 |
| Synonyms | 2310061G07Rik, C4.4A, LY6/PLAUR domain containing 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lypd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- laminin binding
- TFP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lypd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
- negative regulation of smooth muscle cell apoptotic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- laminin binding