RRP36 Gene Summary [Human]

RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).[supplied by OMIM, Jul 2010]

Details

Type
Protein Coding
Official Symbol
RRP36
Official Name
ribosomal RNA processing 36 [Source:HGNC Symbol;Acc:HGNC:21374]
Ensembl ID
ENSG00000124541
Bio databases IDs NCBI: 88745 Ensembl: ENSG00000124541
Aliases ribosomal RNA processing 36
Synonyms C6orf153, dJ20C7.4, ribosomal RNA processing 36
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RRP36 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • rRNA biogenesis protein RRP36

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ocular sarcoidosis
regulates
  • RNR
role in cell
  • molecular cleavage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RRP36 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • 90S preribosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.