SH2D3A Gene Summary [Human]
Predicted to enable guanyl-nucleotide exchange factor activity and phosphotyrosine residue binding activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | SH2D3A |
| Official Name | SH2 domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16885] |
| Ensembl ID | ENSG00000125731 |
| Bio databases IDs | |
| Aliases | SH2 domain containing 3A |
| Synonyms | CT025692.1, Gm46575, NSP1, Sh2d3ap, SH2 domain containing 3A, SH2 domain containing 3A pseudogene |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SH2D3A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src homology 2 (SH2) domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SH2D3A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- small GTPase mediated signal transduction
- JNK cascade
- positive regulation of peptidyl-serine phosphorylation
Molecular Function
What the gene product does at the molecular level
- phosphotyrosine binding
- protein binding
- guanyl-nucleotide exchange factor activity