GPR108 Gene Summary [Human]
Predicted to be involved in negative regulation of toll-like receptor signaling pathway. Located in trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GPR108 |
| Official Name | G protein-coupled receptor 108 [Source:HGNC Symbol;Acc:HGNC:17829] |
| Ensembl ID | ENSG00000125734 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 108 |
| Synonyms | 1810015L19Rik, G protein-coupled receptor 108, LUSTR2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR108 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Lung seven transmembrane receptor
- protein binding
Pathways
Biological processes and signaling networks where the GPR108 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Golgi Apparatus
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPR108 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of toll-like receptor signaling pathway
- transport
- regulation of immune response
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- membrane
- Golgi membrane
- Golgi apparatus
- cis-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding