Gpr108

Involved in negative regulation of toll-like receptor signaling pathway. Acts upstream of or within defense response to virus; protein catabolic process; and type I interferon-mediated signaling pathway. Located in cis-Golgi network membrane. Is active in Golgi apparatus. Orthologous to human GPR108 (G protein-coupled receptor 108). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr108 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gpr108 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr108 gene, providing context for its role in the cell.