LAMP5 Gene Summary [Human]
Predicted to be involved in establishment of protein localization to organelle. Located in endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LAMP5 |
| Official Name | lysosomal associated membrane protein family member 5 [Source:HGNC Symbol;Acc:HGNC:16097] |
| Ensembl ID | ENSG00000125869 |
| Bio databases IDs | |
| Aliases | lysosomal associated membrane protein family member 5, brain and dendritic cell associated LAMP |
| Synonyms | 3110035N03Rik, 6330527O06Rik, BAD-LAMP, C20orf103, lysosomal associated membrane protein family member 5, lysosomal-associated membrane protein family, member 5, RGD1306991, UNC-46 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LAMP5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lysosome-associated membrane glycoprotein (Lamp)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- cellular membrane
- Plasma Membrane
- lysosome
- ER-to-Golgi intermediate compartment
- endosomal membrane
- synaptic vesicles
- growth cone
- synapse
- late endosomes
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LAMP5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- establishment of protein localization to organelle
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- dendrite membrane
- late endosome membrane
- cytoplasmic vesicle membrane
- growth cone membrane
- endosome membrane
- recycling endosome membrane
- synaptic vesicle membrane
- lysosomal membrane
- plasma membrane
- endoplasmic reticulum-Golgi intermediate compartment membrane