IFT22 Gene Summary [Human]

Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in ciliary tip. Predicted to be part of intraciliary transport particle B. Predicted to be active in endomembrane system. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
IFT22
Official Name
intraflagellar transport 22 [Source:HGNC Symbol;Acc:HGNC:21895]
Ensembl ID
ENSG00000128581
Bio databases IDs NCBI: 64792 Ensembl: ENSG00000128581
Aliases intraflagellar transport 22
Synonyms 3110017O03RIK, CFAP9, FAP9, intraflagellar transport 22, RABL5
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IFT22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Signal recognition particle receptor beta subunit
  • Ras of Complex, Roc, domain of DAPkinase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • ciliary tip
  • cilia
  • basal bodies
  • centrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IFT22 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis
  • intracellular protein transport
  • intraflagellar anterograde transport

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cilium
  • endomembrane system
  • intraflagellar transport particle B

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.