TSPAN31 Gene Summary [Human]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]

Details

Type
Processed Transcript
Official Symbol
TSPAN31
Official Name
tetraspanin 31 [Source:HGNC Symbol;Acc:HGNC:10539]
Ensembl ID
ENSG00000135452
Bio databases IDs NCBI: 6302 Ensembl: ENSG00000135452
Aliases tetraspanin 31
Synonyms 2700085A14Rik, SARCOMA AMPLIFIED SEQUENCE, SAS, tetraspanin 31
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSPAN31 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Tetraspanin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dedifferentiated liposarcoma
  • organismal death
  • well-differentiated liposarcoma
  • soft tissue sarcoma cancer
regulated by
regulates
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TSPAN31 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell proliferation

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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