RANBP6 Gene Summary [Human]

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RANBP6
Official Name
RAN binding protein 6 [Source:HGNC Symbol;Acc:HGNC:9851]
Ensembl ID
ENSG00000137040
Bio databases IDs NCBI: 26953 Ensembl: ENSG00000137040
Aliases RAN binding protein 6
Synonyms C630001B19, RAN binding protein 6
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RANBP6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Importin repeat
  • HEAT repeat
  • HEAT-like repeat
  • protein binding
  • Importin repeat 6
  • HEAT repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • B-cell non-Hodgkin disease
  • mature B-cell neoplasia
  • Burkitt lymphoma
regulated by
  • NUPR1
  • D-alpha-hydroxyglutarate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Mitochondria
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RANBP6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein import into nucleus

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • synapse

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • nuclear localization sequence binding

Gene-Specific Assays for Results You Can Trust

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