IKBIP Gene Summary [Human]
Predicted to be involved in response to X-ray. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IKBIP |
| Official Name | IKBKB interacting protein [Source:HGNC Symbol;Acc:HGNC:26430] |
| Ensembl ID | ENSG00000166130 |
| Bio databases IDs | |
| Aliases | IKBKB interacting protein, I kappa B kinase interacting protein |
| Synonyms | 1200009F10Rik, 1700023M03Rik, FLJ31051, IKBKB interacting protein, IKIP, RGD1305457 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IKBIP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- Barrett syndrome
- lung injury
- mantle cell lymphoma
- dextran sodium sulfate-induced colitis
role in cell
- phosphorylation in
- expression in
- activation in
- binding in
- cellular infiltration by
- interaction in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IKBIP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to X-ray
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding