STRIP1 Gene Summary [Human]
This gene encodes a member of the striatin-interacting phosphatase and kinase complex, which is involved in localization of the Golgi body. The encoded protein participates in cytosketelal organization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Details
| Type | Protein Coding |
| Official Symbol | STRIP1 |
| Official Name | striatin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:25916] |
| Ensembl ID | ENSG00000143093 |
| Bio databases IDs | |
| Aliases | striatin interacting protein 1, FAR11 factor arrest 11 homolog A (yeast) |
| Synonyms | 6330569M22Rik, 6530401O14Rik, FAM40A, Fam50a, FAR11A, striatin interacting protein 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STRIP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase binding
- protein binding activity, bridging
- enzyme binding
- Domain of unknown function (DUF3402)
- protein binding
- N1221-like protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STRIP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cortical actin cytoskeleton organization
- negative regulation of hippo signaling cascade
- regulation of cell morphogenesis
- cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein binding
- small GTPase binding
- protein binding, bridging