Strip1 Gene Summary [Mouse]
Enables protein kinase binding activity and small GTPase binding activity. Predicted to be involved in cortical actin cytoskeleton organization; negative regulation of hippo signaling; and regulation of cell morphogenesis. Predicted to be located in nucleus. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytosol. Is expressed in nervous system. Orthologous to human STRIP1 (striatin interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Strip1 |
| Official Name | striatin interacting protein 1 [Source:MGI Symbol;Acc:MGI:2443884] |
| Ensembl ID | ENSMUSG00000014601 |
| Bio databases IDs | |
| Aliases | striatin interacting protein 1 |
| Synonyms | 6330569M22Rik, 6530401O14Rik, FAM40A, Fam50a, FAR11A, striatin interacting protein 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Strip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase binding
- protein binding activity, bridging
- enzyme binding
- Domain of unknown function (DUF3402)
- protein binding
- N1221-like protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Strip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cortical actin cytoskeleton organization
- negative regulation of hippo signaling cascade
- regulation of cell morphogenesis
- cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein binding
- small GTPase binding
- protein binding, bridging