MRPL9 Gene Summary [Human]

This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014]

Details

Type
Protein Coding
Official Symbol
MRPL9
Official Name
mitochondrial ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:14277]
Ensembl ID
ENSG00000143436
Bio databases IDs NCBI: 65005 Ensembl: ENSG00000143436
Aliases mitochondrial ribosomal protein L9
Synonyms 8030480E20Rik, bL9m, C330013D18Rik, L9mt, mitochondrial ribosomal protein L9
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MRPL9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ribosomal protein L9
  • protein binding
  • Ribosomal protein L9, N-terminal domain
  • translation regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • nonalcoholic fatty liver disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Nucleus
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MRPL9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial ribosome
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.