MTG1 Gene Summary [Human]
Enables GTPase activity. Involved in regulation of mitochondrial translation and regulation of respiratory system process. Located in mitochondrial inner membrane and mitochondrial ribosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MTG1 |
| Official Name | mitochondrial ribosome associated GTPase 1 [Source:HGNC Symbol;Acc:HGNC:32159] |
| Ensembl ID | ENSG00000148824 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosome associated GTPase 1 |
| Synonyms | Gm169, GTP, GTPBP7, mitochondrial ribosome-associated GTPase 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MTG1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribosome biogenesis GTP-binding protein YlqF
- GTPase
- enzyme
- protein binding
- Circularly permuted YlqF-related GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MTG1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of respiratory system process
- mitochondrial translation
- regulation of mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- mitochondrial ribosome
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity