CAMKMT Gene Summary [Human]
This gene encodes a class I protein methyltransferase that acts in the formation of trimethyllysine in calmodulin. The protein contains a AdoMet-binding motif and may play a role in calcium-dependent signaling. [provided by RefSeq, Sep 2012]
Details
| Type | Protein Coding |
| Official Symbol | CAMKMT |
| Official Name | calmodulin-lysine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:26276] |
| Ensembl ID | ENSG00000143919 |
| Bio databases IDs | |
| Aliases | calmodulin-lysine N-methyltransferase, CaM KMT |
| Synonyms | 1700106N22Rik, AI480743, C2orf34, calmodulin-lysine N-methyltransferase, Cam, CLNMT, KMT, RGD1310453 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CAMKMT often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calmodulin-lysine N-methyltransferase
- heat shock protein binding
- enzyme
- AdoMet_MTases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- Golgi Apparatus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CAMKMT gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrion organization
- regulation of rhodopsin mediated signaling pathway
- methylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- Golgi apparatus
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- heat shock protein binding
- calmodulin-lysine N-methyltransferase activity