Camkmt Gene Summary [Mouse]

Enables calmodulin-lysine N-methyltransferase activity. Acts upstream of or within mitochondrion organization and peptidyl-lysine methylation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of protein-containing complex. Is expressed in gonad; maxillary process; ovary; and testis. Used to study hypotonia-cystinuria syndrome. Orthologous to human CAMKMT (calmodulin-lysine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Camkmt
Official Name
calmodulin-lysine N-methyltransferase [Source:MGI Symbol;Acc:MGI:1920832]
Ensembl ID
ENSMUSG00000071037
Bio databases IDs NCBI: 73582 Ensembl: ENSMUSG00000071037
Aliases calmodulin-lysine N-methyltransferase
Synonyms 1700106N22Rik, AI480743, C2orf34, calmodulin-lysine N-methyltransferase, Cam, CLNMT, KMT, RGD1310453
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Camkmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calmodulin-lysine N-methyltransferase
  • heat shock protein binding
  • enzyme
  • AdoMet_MTases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • major depression
  • bipolar disorder
  • proteinuria
  • cholelithiasis
  • metabolic syndrome X
regulated by
  • geldanamycin
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • Golgi Apparatus
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Camkmt gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrion organization
  • regulation of rhodopsin mediated signaling pathway
  • methylation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol
  • Golgi apparatus
  • macromolecular complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • heat shock protein binding
  • calmodulin-lysine N-methyltransferase activity

Gene-Specific Assays for Results You Can Trust

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